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1.
Materials (Basel) ; 16(12)2023 Jun 15.
Artigo em Inglês | MEDLINE | ID: mdl-37374579

RESUMO

A novel clay-coated mesh was fabricated via a simple brush-coating method without the use of special equipment, chemical reagents, and complex chemical reactions and operation processes. Possessing superhydrophilicity and underwater superoleophobicity, the clay-coated mesh can be used for efficiently separating various light oil/water mixtures. The clay-coated mesh also exhibits excellent reusability, maintaining a high separation efficiency of 99.4% after 30 repeated separations of the kerosene/water mixture.

2.
Membranes (Basel) ; 13(3)2023 Feb 26.
Artigo em Inglês | MEDLINE | ID: mdl-36984663

RESUMO

Soil-coated fabrics were fabricated by scrape-coating of soil slurry onto cotton fabrics. The raw materials, soil, and cotton fabrics were, respectively, obtained from farmland and waste bed sheets, making the method a zero-material cost way to produce superwetting membrane. The superhydrophilic/underwater superoleophobic soil-coated fabrics exhibit high efficiency (>99%), ultra-high flux (~45,000 L m-2 h-1), and excellent antifouling behavior for separating water from various oils driven by gravity. The simple fabrication and superior performance suggest that the soil-coated fabric could be a promising candidate as a filtration membrane for practical applications in industrial oily wastewater and oil spill treatments.

3.
Res Vet Sci ; 156: 1-6, 2023 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-36706696

RESUMO

PURPOSE: This study evaluated pathogenic effect of TGF-ß1/Smad3 pathway in mouse model after infecting them with HPI+ and HPI- strains of Escherichia coli (E. coli) which were isolated from diarrhea in calves. METHODS: Kunming mice were randomly divided into 3 groups: a control group, HPI+-infection group and HPI--infection group. After intraperitoneal injection of HPI strains of E. coli (concentration: 3 × 108 cfu/mL) in mice, alanine aminotransferase (ALT) and aspartate aminotransferase (AST), tumour necrosis factor-α (TNF-α) and interleukin-6 (IL-6) contents were detected at 12 h post infection. The sections of liver and kidney were obtained for histopathological observations. Propidium iodide and 4',6-diamidino-2-phenylindole (DAPI) staining was used to analyze the cell apoptosis. The immunohistochemistry staining and quantitative real time PCR (q-PCR) were performed for evaluating the protein and mRNA expression of TGF-ß1, Collagen I and Smad3. The histological change and PI staining of liver and kidney showed significant injuries. Compared with the control group, the serum ALT and AST activities and TNF-α and IL-6 contents of mice in the HPI+ and HPI- groups were increased, number of apoptotic cells and expression of TGF-ß1, Collagen Iand Smad3 were up-regulated after E. coli infection in liver and kidney, which was significantly increased in HPI+-infected compared to HPI-. CONCLUSION: The study concludes that E. coli HPI induced and enhanced the over expression of TGF-ß1/Smad3 pathway and ultimately caused pathological anomalies.


Assuntos
Doenças dos Bovinos , Animais , Bovinos , Camundongos , Doenças dos Bovinos/genética , Diarreia/genética , Escherichia coli/genética , Ilhas Genômicas , Interleucina-6/genética , Fator de Crescimento Transformador beta1/genética , Fator de Crescimento Transformador beta1/metabolismo , Fator de Necrose Tumoral alfa/genética , Modelos Animais
4.
ACS Appl Mater Interfaces ; 13(10): 12322-12330, 2021 Mar 17.
Artigo em Inglês | MEDLINE | ID: mdl-33683113

RESUMO

A series of hole transporting materials (HTMs) with fused tetraphenylethylene cores (9,9'-bifluorenylidene and dibenzo[g,p]chrysene) as well as different substitution positions of arylamine side arms has been designed and synthesized. A reference HTM with a non-fused tetraphenylethylene core is also prepared for a comparative study. It is noted that fused tetraphenylethylene molecules show a bathochromic spectral shift, electronegative character, and lower reorganization energies than the non-fused ones. Furthermore, the molecules with side arms located on the meta-position on the tetraphenylethylene core in terms of a double bond exhibit a deeper highest occupied molecular orbital level than those of the para-position-based ones whether tetraphenylethylene is fused or not. Moreover, the reorganization energies of fused meta-position-based HTMs are lower than those of para-position-based HTMs. Fused tetraphenylethylene HTMs own a better hole-extraction capability than the non-fused ones. When used in perovskite solar cells, all devices with fused tetraphenylethylene HTMs display better performance than those of the non-fused ones. The HTMs based on dibenzo[g,p]chrysene exhibit better performance than those of bifluorenylidene. Moreover, the devices with HTMs with side arms located on the meta-position on the tetraphenylethylene core display higher power conversion efficiency than those of the para-position-based ones. The results give some new insight and reference to develop ideal HTMs for perovskite solar cells.

5.
Microb Pathog ; 135: 103621, 2019 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-31310831

RESUMO

Astragalus polysaccharides (APS) are a traditional Chinese medicine with a therapeutic effect by enhancing immune function; however, the underlying functional mechanism is still unclear. The aim of the present study was to determine the effect of oral administration of APS on jejunum mucosal immunity in chickens vaccinated against Newcastle disease (ND). One-day-old Hy-Line male chickens were divided into five groups of 20 chicks each: three APS groups, one vaccinated control (VC) group and one non-vaccinated negative control (NC) group. On d 10, the APS groups were orally administered 0.5 mL of APS at doses of 1 mg/mL (APSL), 2 mg/mL (APSM) and 4 mg/mL (APSH) daily for 4 consecutive days. The chicks in the control groups were administered 0.5 mL saline for those 4 days. All groups except NC were administered a ND virus (NDV) vaccine on day 14. The jejunum was removed from 4 randomly selected chickens of each group at 1, 7, 14 and 28 days after vaccination. The jejunal villus height (VH) and crypt depth (CD) were measured and the VH:CD ratio calculated. Immunohistochemistry was used to analyze the differences of IgA+ cells in the jejunum. NDV specific secretory IgA (sIgA) levels in jejunal contents were detected using an indirect ELISA. At most time points, VH:CD ratios, number of IgA+ cells, and sIgA levels were significantly higher in the APS groups than those in VC and NC groups, but there were little differences among the three doses of APS groups. These results indicate that oral administration of APS could enhance the intestinal mucosal immune function of chickens, and APS could be used as a vaccine enhancer.


Assuntos
Astrágalo/química , Galinhas/imunologia , Imunidade nas Mucosas/efeitos dos fármacos , Jejuno/efeitos dos fármacos , Doença de Newcastle/imunologia , Polissacarídeos/administração & dosagem , Vacinação/veterinária , Administração Oral , Animais , Modelos Animais de Doenças , Imunoglobulina A Secretora , Jejuno/patologia , Masculino , Medicina Tradicional Chinesa , Vírus da Doença de Newcastle/imunologia , Extratos Vegetais/administração & dosagem
6.
Biomed Res Int ; 2016: 7059196, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26966688

RESUMO

Little is known about Coxiella burnetii infection among cattle farmers and farm residents in China. Thus, the present study was conducted to detect the seroprevalence of C. burnetii infection and estimate associated risk factors among cattle farmers and farm residents in China. A cross-sectional study was designed, and sera of 362 people living or working on 106 cattle farms were tested for C. burnetii IgG and IgM antibodies by immunofluorescence assay. Overall C. burnetii seroprevalence was 35.6% (129/362, 95% CI: 30.70-40.57), and 112 participants had experienced a past infection and seventeen (4.7%) had experienced a relatively recent infection. In the final combined multilevel model, the following activities were significantly associated with presence of antibodies against C. burnetii: milking cattle, providing general healthcare to cattle, providing birth assistance, contact dead-born animals, urbanization, and presence of mice and/or rats in the stable. Moreover, presence of disinfection equipment was a significant protective factor. This is the first study addressing the seroprevalence and risk factors of C. burnetii infection in cattle farmers and farm residents in three northeastern provinces and Inner Mongolia Autonomous Region, China.


Assuntos
Anticorpos Antibacterianos/isolamento & purificação , Coxiella burnetii/isolamento & purificação , Febre Q/microbiologia , Estudos Soroepidemiológicos , Adulto , Animais , Anticorpos Antibacterianos/imunologia , Bovinos , China , Coxiella burnetii/imunologia , Coxiella burnetii/patogenicidade , Fazendeiros , Feminino , Humanos , Masculino , Camundongos , Pessoa de Meia-Idade , Leite/microbiologia , Febre Q/imunologia , Febre Q/patologia , Ratos , Fatores de Risco
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